Darragh Charles

  • To the authors’ knowledge, the current study comprises the most ticks reported from naturally infested domestic cats in the United States to date. The 373 ticks identified account for greater than 70% of all primary reports of ticks naturally infesting U.S. domestic cats. Over eighteen percent (18.7%) of cats examined were infested with ticks, w…[Read more]

  • Darragh Charles posted an update 3 months ago

    AcknowledgmentsIntroductionSeveral viruses use cell-cell adhesion molecules from the immunoglobulin (Ig) superfamily as receptors to enter target Ion Channel Compound Library (Dermody et al., 2009). In many cases, the interaction with the viral ligand requires the disruption of the receptor trans-interaction at intercellular contacts (Stehle and…[Read more]

  • Heat shock proteins (Hsps) have been identified in organisms from bacteria to eukaryotes and show protein sequence conservation across species. They are important in many cellular processes, including development, growth, protein folding, signal transduction and apoptosis. They play key roles in response to stress conditions such as thermal…[Read more]

  • IntroductionHerpes zoster (HZ), a painful and debilitating disease seen most often in the elderly and immune compromised, is the clinical manifestation of reactivation of the human alphaherpesvirus Varicella Zoster Virus (VZV) from a neuronal latent state that was established during the primary infection, chickenpox (varicella). HZ affects about a…[Read more]

  • Darragh Charles posted an update 4 months ago

    A recent study examining experimental infections of C and S strains in 1.5-month-old Assaf lambs found that specific antibody and interferon gamma (IFNγ) production was significantly greater in animals infected with the C strains, with no consistent IFNγ responses observed in animals infected with S-type strains (Fernandez et al., 2014). Lambs i…[Read more]

  • The present Russian economic system may be characterized as a hybrid of the old Soviet heritage with inefficient state-owned or state-controlled subsidized enterprises and state intervention, on the one hand, and a market economy consisting mainly of the small and medium-sized business sector that evolved after the change of system, on the other…[Read more]

  • Recently, it was proposed that some Chilodonella species may comprise cryptic species complexes given discordance between morphological descriptions and genetic analyses (Mitra et al., 2013; Warren, 2013). Cryptic species can be grouped by shared morphology, but advances in molecular studies have revealed divergence in genetic loci characterising…[Read more]

  • The IFI56 encodes a member of the IFN-stimulated gene 56 (ISG56, official gene symbol IFIT1, also known as P56 protein) family, whose homologs are evolutionarily conserved from cannabinoid receptors to mammals (Chebath et al., 1983; Kusari et al., 1987). While the IFI56 gene is normally silent in most cell types, its transcription is strongly…[Read more]

  • ConclusionsEP is a disease of clinical and economical relevance worldwide. Despite the efforts made to control the geographic expansion of the disease, the epidemiology of Piroplasms infection is constantly evolving. The results of this work evidence how horses can be infected with Piroplasms species different from T. equi and B. caballi.…[Read more]

  • In 1961 Shults described another subspecies Alveococcus (=Echinococcus) multilocularis kazakhensis, from Kazakhstan and Russia, which exhibited multilocular development but infected the domestic dog as DH, and sheep and pigs as IH, thus differing from the nominal E. multilocularis which infects rodents as IH (from Kumaratilake and Thompson, 1982).…[Read more]

  • In recent years, some topical (spot-on, spray, shampoo, emulsion) formulations containing fatty acids, other lipids (such as ceramides) and non-lipid ingredients have been advocated for dogs affected with AD (Marsella et al., 2012; Blaskovic et al., 2014). Although they can increase epidermal lipid lamellae (Piekutowska et al., 2008) and no…[Read more]

  • Finding of T. gondii Asiatic acid in adult bears in the present study is in accord with previous surveys indicating that the prevalence of T. gondii in bears in Pennsylvania is very high, consistent, and intriguing. In contrast to sows, T. gondii antibodies were not detectable in sera of 63 cubs sampled at 7–8 weeks of age, while still in t…[Read more]

  • Ocular lipid deposition can also be linked to other vascular-related factors; for example, lipid laden aqueous is more likely to be seen in kittens than mature cats, as the iris microvessels are more permeable. The fragility of the blood aqueous barrier varies between species and breakdown of the blood-aqueous barrier can occur, for example, due…[Read more]

  • Darragh Charles posted an update 5 months ago

    One of the objectives of this study was to assess the analgesia provided post-operatively by the two agents. There are no data comparing buprenorphine and morphine for analgesic purposes in horses on clinical patients. Therefore, an a priori power calculation was not performed. The retrospective power calculation determined that 97 horses per…[Read more]

  • Darragh Charles posted an update 5 months ago

    1. IntroductionAMP-activated protein kinase (AMPK) is an enzyme with a central role in cellular energy homeostasis that is activated in response to a change in the cellular balance of AMP to ADP/ATP. Often described as the cell’s fuel gauge, it becomes activated in response to cellular stressors including inflammation, hypoxia and oxidant stress…[Read more]

  • Potential energies for interaction between pairs of identical SWNTs, γ=μ/2 Download high-res image (157KB)Download full-size imageFig. 5. Potential energies for interaction between pairs of identical SWNTs, γ = μ/2.Reprinted with permission from reference Zhbanov, Pogorelov, and Chang (2010).3.2. Grease based on grapheneIn addition to SWNTs and…[Read more]

  • 2. Material and methodology2.1. Study areaThe impacts of climate change were also observed, from a global warming perspective, in Jiangsu GEF project areas. The increasing rate of temperature was 0.26°C per decade from 1961 to 2008 and has risen to 0.58°C per decade since the 1990s. Annual nobiletin fluctuated with an increasing trend of 2.9 mm p…[Read more]

  • Ubicado de origen o destino de tráfico de cocaína + 3.71aUbicado en rutas de tráfico de metanfetaminas + 3.45aUbicado en rutas de tráfico de heroína + 3.03aProporción de delitos contra la salud + 3.75Prevalencia estatal del consumo de drogas en jóvenes + 3.84Prevalencias estatal del consumo de cocaína + 3.75Prevalencia estatal del consumo de mari…[Read more]

  • Thus, two divergent groups of mtDNA haplotypes and nDNA Autophagy Compound Library in mallards and spot-billed ducks in Eurasia have been identified. These findings can be interpreted as evidence of hybridization between the Mallard and Spot-billed Duck in the south of the Russian Far East. Nevertheless, the alternative hypothesis of the…[Read more]

  • ResultsParticipants’ CharacteristicsTable 1 shows the clinical characteristics of all the participants (n = 172).Excursions and Peak Motion Speeds of the Bilateral DiaphragmUnivariate Analysis of Associations Between the Diaphragmatic Excursions and Participants’ DemographicsFigure 3. Estimated regression line of the excursion of the prostaglandi…[Read more]

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