Darragh Hartley

  • In 2005, the SARS-CoV 22-kDa nsp8 was shown to form a ring-like complex together with the 12-kDa nsp7 (Zhai et al., 2005) (Fig. 4A–C). This complex consisted of 8 copies of each subunit, oriented such that the inner cavity of the ring was positively charged and capable of binding RNA (Zhai et al., 2005) (Fig. 4A). Given the structural similarity o…[Read more]

  • Darragh Hartley posted an update 1 month ago

    Material and methodsResultsDiscussionChina is a developing country that holds the largest population in the world. With continued improvement of sanitation levels and widespread HAV vaccination in this country, the incidence of hepatitis A has declined in recent years. However, infection by HAV remains the major cause of acute viral hepatitis,…[Read more]

  • ConclusionTaken together, our results suggest that the effective reference frame for motion perception involves a combination of motion-based, retinotopic and spatiotopic reference frames. Relative motions defined by motion-based reference frames dominate retinotopic and spatiotopic motions. Effectiveness of the motion-based reference frames drops…[Read more]

  • CD62L is characteristically found on cells of the immune system and has not generally been reported in solid-organ tumors. In nonsolid tumors such as in lymphoma, CD62L has been shown to play a critical role in the development of metastasis. In a study evaluating the role of CD62L on lymphomagenesis and dissemination, Belanger reported that…[Read more]

  • We attempted to determine the group of patients that would experience a poor renal outcome. There were no significant preoperative conditions that could be used to predict renal outcome. As for the 10 patients who required hemodialysis after the surgery, significant predisposing factors (Table 3) were not observed. However, it was observed that…[Read more]

  • Darragh Hartley posted an update 2 months ago

    Cell-based vaccines, in general have been produced using egg grown candidate viruses. It has been reported that it would be a major advantage to dispose of candidate vaccine viruses that are grown in cell culture (Zhang et al., 2011; Reed, 1938). This is because the use of egg grown candidate viruses could be a constraint if the subsequent vaccine…[Read more]

  • For monolithic zirconia, regardless of thickness, DC values of resin cements were significantly different. When resin cements cured under veneered zirconia, Zirconite showed significantly highest DC value among resin cements. The DC value of Variolink II dual-cured was significantly lower compared with Variolink II light-cured and Zirconite under…[Read more]

  • The settling and hardening reactions take place at room temperature, but sometimes slightly elevated curing temperatures (up to 80°C) are used to enhance some properties. Hardened products may possess mechanical properties comparable to ordinary Portland cement concrete (OPC) or even better. Geopolymers exhibit good thermal and fire resistance of…[Read more]

  • Although CPV can be maintained in the environment for months (McCaw and Hoskins, 2006), a recent study has shown that CPV can be transmitted not only by direct contact but also through vectors such as flies (Bagshaw et al., 2014). A high amount of waste in urban areas could lead to higher concentration of flies at these sites than in rural areas,…[Read more]

  • Darragh Hartley became a registered member 2 months, 3 weeks ago