Mike Alstrup

  • Mike Alstrup posted an update 4 months ago

    To date, eliciting anti-MPER bnAbs through vaccination has been elusive. Several approaches have been examined, including (1) immunization with short MPER peptides either alone or coupled to carrier proteins (Decroix et al., 2001; Joyce, 2002; Liao et al., 2000; Matoba et al., 2006; McGaughey et al., 2003; Ni et al., 2004), (2) neutralizing…[Read more]

  • Mike Alstrup posted an update 4 months ago

    Overall, we did see a T. suis-associated Type 2 dominant immune response at day 35 and 71p.i. in the double infected group OT, corresponding to a T. suis dominant response associated with reduced T. suis and O. dentatum worm burden. However, we found a lower expression of IL-13, presumably the primary mediator of T. suis expulsion mechanisms,…[Read more]

  • Mike Alstrup posted an update 4 months ago

    Inactivated vaccines became commercially available in the USA in 1945, but were not adopted by the poultry industry at that time as they were comparatively expensive, and were unable to prevent clinical disease to a sufficient level to merit wide spread use. The first live vaccines licensed in 1948 were formulated with strains now designated as…[Read more]

  • The Capitalist economies in the West had grown stronger and thus their pace of development was sharp and quick, Soviet people, therefore, were forced to believe that open market economies were remedies for backwardness and growth. Ronald Reagan in fact forced Soviets to such a mad race of armament that it could not keep pace with the West.…[Read more]

  • Our present results on PK-15 and STEC fk 506 indicate that at least a portion if not all of the Vlp family members are involved in M. hyorhinis cytoadhesion to host cells. Two different methods were applied to identify the adhesion ability of the Vlp family, the inhibition of the cytoadhesion of mycoplasmas by purified rVlp proteins and the…[Read more]

  • Proteomic analysis showed that energy metabolism and cytoskeleton related proteins are significantly perturbed after Salmonella infection. In fact, we observed the down regulation of enzymes such as ATP5B, UQCRC1 and CKB involved in oxidative phosphorylation, and of GAPDH, involved in gluconeogenesis/glycolysis, which could suggest a reduction of…[Read more]

  • Bickbau [32] discussed the implementation of the low-clinker nano cements technology and showed that there is a real opportunity to reduce cost per tonne of cement by 40–60kg unit fuel, improve the cement quality and increase the production in any cement plant without constructing clinker burning steps. This will decrease emissions of the o…[Read more]

  • A uniformly flocked saddle, fitted with even contact and fitted in balance, was associated with larger dimension changes in the middle third of the saddle region compared with other saddles. The balance of the saddle was the most influential factor for changes in back width in the cranial third of the saddle region. A saddle tipping back or…[Read more]

  • ResultsDiscussionCurrently, protection of pigs against IAV relies primarily on the use of inactivated vaccines, most commonly in breeding females (Vincent et al., 2008b). Sows vaccinated prior to farrowing often have high HI antibody titers against vaccine virus(es) that may lead to long-lasting maternally-derived anti-IAV ARQ 621 in piglets…[Read more]

  • Reductions have also been observed in gene complements that are implicated in the patterning of body plans in animals. Cestodes have the most reduced set of homeobox genes of any studied bilaterian animal and specifically lost several ParaHox genes that are ancestrally involved in the specification of a through-gut (Koziol et al., 2009; Tsai et…[Read more]

  • Histone acetyltransferase TIP60 (dTip60 in Drosophila) is part of a multimeric protein complex that unites HAT with chromatin remodeling activities that include both gene repression and activation. dTip60 is involved in widespread gene regulation in Drosophila, especially genes involved in chromatin-related functions (Schirling et al., 2010).INO80…[Read more]

  • The PRRSV nucleotide substitution rate has been estimated to vary between 4.7×10−2 and 1.55×10−3 (Murtaugh et al., 2010; Yoon et al., 2012). There is growing evidence of recombination from both in vitro (van et al., 2001) and in vivo studies, in experimental and field conditions (Li et al., 2009; Lu et al., 2015; Shi et al., 2013). In this study…[Read more]

  • Previous studies demonstrated that virulent TGEV causes significant inflammation in intestinal tissues, and animal death is mainly attributed to the extreme imbalance of Na+ and K+ ions caused by the severity of the clinical symptoms (Cruz et al., 2013; Saif, 1996). Thus, inflammatory injury to intestinal tissue caused by an overactive immune…[Read more]

  • The initial ultrasound suggested placental retention, but the pathology examination of the placenta showed that the actual cause was subinvolution of the placental bed. Only a few published cases discuss this subinvolution [12–15]. It may be an underestimated cause of severe late PPH and can lead to hysterectomy [14]. It may have promoting f…[Read more]

  • Coinfections with more than one CIRD agent occurred in 9 animals, all of which were early acute clinically ill, and included two triple infections with B. bronchiseptica, M. cynos and CPIV, two dual infections with B. bronchiseptica and M. canis and single cases of coinfections with B. bronchiseptica, M. canis and CnPnV, M. cynos and CRCoV, M.…[Read more]

  • In northern India, T. evansi is transmitted mechanically by biting hematophagous flies (Tabanids) (Sumba et al., 1998) and T. equi is mainly transmitted by longistrate tick, Hyalomma anatolicum anatolicum, causing significant morbidity and mortality in equids (Kumar et al., 2007). As the bch of both the diseases are habitual to hot plain areas of…[Read more]

  • Recently, Fitzgibbon et al. (2010) demonstrated a prevalence of 88% for cemental hypoplasia or altered infundibular cementum in healthy CT. Similarly high prevalence rates ranging from 43% (Baker, 1974) to 90% (Windley et al., 2009a) were reported in other studies. There is general agreement that an infundibulum with an incomplete cemental f…[Read more]

  • To the authors’ knowledge this paper is the first to describe the use of PNA FISH to detect biofilm in wound samples from horses. To detect biofilm it is necessary to directly visualize the bacterial 5-aminosalicylic acid and the gold standard for this is PNA FISH and visualization using CLSM (Burmølle et al., 2010). Bacteria are unevenly di…[Read more]

  • Analysis of the effects of future climate change has the same limitations encountered when considering current and past data. It is not yet possible to relate the relevance of Malone’s risk index to New Zealand and hence a definitive verdict on the severity of F. hepatica infections over the next several decades cannot be easily predicted. H…[Read more]

  • Mike Alstrup posted an update 6 months ago

    ResultsTable 1 shows the characteristics of patients in relation to gender, age, BMI, number (%) of patients submitted to prior colonoscopy, how many had adequate colon preparation and how many patients had buy Tedizolid HCl complete examination. Patients with complications had adequate colon preparation and a complete examination.Table 1.…[Read more]

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