Brin Oneill

  • Brin Oneill posted an update 1 week, 1 day ago

    Plants, insects and viruses: intimate relationshipsOther than through seed dispersal most plants do not move across significant distances; hence their horizontally-transmitted viruses must be moved by others. Most often the vectors for plant viruses are insects, although below ground transmission also occurs through nematodes, chytrids or…[Read more]

  • Brin Oneill posted an update 1 week, 5 days ago

    The activities of the promoters of ACMV in response to co-transformation with any of the ACMV ORF-constructs in N. clevelandii protoplasts indicated that, in addition to the promoter of AC2, the promoter of AV1 ORF was also activated by AC3, although to a lesser extent. The same pattern of AC1-repression and activation of AC2 and AV1 promoters…[Read more]

  • Brin Oneill posted an update 1 week, 6 days ago

    IntroductionThe genus Angiostrongylus (Strongylida, Angiostrongylidae) includes at least 21 species of nematodes infecting the lungs and blood vessels of a variety of mammals including insectivores, rodents, felids and canids (Anderson, 2000; Spratt, 2015). Angiostrongylus costaricensis is the zoonotic agent of abdominal angiostrongyliasis, which…[Read more]

  • Brin Oneill posted an update 3 weeks, 1 day ago

    ConclusionsHuman herpesviruses express multiple proteins during the immediate-early, early, and late phases of the virus replication cycle and during latency that activate the PI3K/Akt pathway. Activation of PI3K/Akt by viral glycoproteins such as gB in HSV, CMV, and KSHV, HSV gD, and EBV gp350, as well as tegument proteins of HSV and VZV present…[Read more]

  • Brin Oneill posted an update 3 weeks, 4 days ago

    CRM-1, a key export receptor, is required for cargo proteins containing a leucine-rich nuclear export sequence to travel from the nucleus to the cytoplasm. LMB is a specific inhibitor of CRM-1-mediated nuclear export and could block the exit process of NSP1α (Fig. 3A). The Co-IP experiment revealed that NSP1α interacted with CRM-1, and this i…[Read more]

  • Brin Oneill posted an update 3 weeks, 4 days ago

    Relating aging and mtDNAA reduction in mitochondrial ATP production could contribute to reduced endurance and muscle weakness. Increased mtDNA oxidative damage with aging and cumulative DNA damage could explain an overall reduction in mtDNA copy numbers in oxidative tissue, such as skeletal muscle. A reduced mtDNA copy number may contribute to…[Read more]

  • Brin Oneill posted an update 4 weeks ago

    Live-cell imaging was only recently used to follow trafficking and dynamics of coronavirus proteins. Fluorescent tags such as GFP or mCherry were appended to nsp2, nsp4 or N proteins to study replication–transcription complexes and their relationship to formation of membrane structures in virus-infected Cardiogenol C (Freeman et al., 2014; H…[Read more]

  • Brin Oneill posted an update 4 weeks, 1 day ago

    The current study intended to compare the FERT and EHA in estimating the efficacy of albendazole, triclabendazole, oxyclozanide and praziquantel against Fasciola spp. infection in cattle.Materials and methodsResultsDiscussionFor estimation of Fasciola spp. susceptibility to anthelmintics, fecal egg reduction test (FERT) is the most often used with…[Read more]

  • Brin Oneill became a registered member 4 weeks, 1 day ago