Hilton Lunde

  • In the following, we re-analyze the FECs data from the Swedish sheep study using our proposed model. The worm burden differs depending on the animals and the type of caged compounds eggs that is being counted, hence the choice of hyperparameters for the prior should be based on similar studies. According to another study of the distribution of…[Read more]

  • Although only rarely reported in literature, pododermatitis is a common problem in zoo and circus elephants with as many as 50% of the captive population being affected, especially among Asian elephants (Fölsch, 1968; Fowler, 1993; Mikota et al., 1994; Keet et al., 1997; Lewis et al., 2010). The aetiology of pododermatitis in wild elephants was…[Read more]

  • Hilton Lunde posted an update 1 week, 4 days ago

    Despite that only 4 of 11A(H5N1) viruses showed a high-virulence phenotype in ferrets, all viruses replicated to high titers in the respiratory tract and, with few exceptions, all viruses were capable of limited replication in brain tissues examined. Further systemic spread of these viruses was observed only sporadically in intestinal and spleen…[Read more]

  • Hilton Lunde posted an update 1 week, 5 days ago

    Using global G sequences under exclusion of the Lomustine region, the previously reported time of origin of the Australian lineage (Trinidad et al., 2014) could be confirmed in this study (Fig. 1), suggesting the data be reliable for estimating the time of origin of global BEFV. According to Bayesian analysis, we traced the East Asian lineage…[Read more]

  • Hilton Lunde posted an update 2 weeks ago

    ConclusionsJapanese encephalitis virus is primarily a cause of human encephalitis and is endemic throughout Asia, especially where environmental conditions promote abundance of the main mosquito vector, Cx. tritaeniorhyncus. However, a range of domestic animals are susceptible to disease. In addition, livestock losses in the form of foetal…[Read more]

  • Materials and methodsResultsDiscussionIn this report, the gene encoding the protein termed B. ovis surface protein D (BoSPD) was cloned and used to detect B. ovis in sheep and ticks. The BoSPD sequence shared limited similarity with T. annulata Protein D (Schneider et al., 2004), Theileria parva CD8+ T cell target antigen Tp2 (Graham et al.,…[Read more]

  • Random transposon mutagenesis, which allows screening for attenuated mutants in an animal model of infection at the genome-wide level, is one of the most powerful technologies for mining of potential virulence-associated genes. The use of this technology has led to the identification of new virulence genes in several pathogenic bacteria. In our…[Read more]

  • Hilton Lunde posted an update 3 weeks ago

    Fig. 2 shows a contact mode AFM height image and series of nanoscale thermal analysis curves recorded on the seven-layer cling film cross section. The colored marker locations on the AFM image (spaced 1μm apart) represent locations where the nanothermal measurements were recorded. The red marker locations/thermal curves with lower transition…[Read more]

  • Unlike Bcl-2, which is highly expressed in naïve and memory T CB-5083 and rapidly downregulated after T cell activation, Mcl-1 expression is strongly induced after TCR stimulation (Dunkle et al., 2011; Opferman et al., 2003). Therefore, Mcl-1 is believed to maintain T cell viability during antigen-driven proliferation, especially when Bcl-2…[Read more]

  • Materials and methodsResultsDiscussionThe study reported here used an RLB assay to determine the prevalences of tick-borne infections in an intensively studied cohort of indigenous calves in a smallholder, mixed crop/livestock farming system in western Kenya, an important farming sytem in eastern Africa. The results are in general agreement with…[Read more]

  • Hilton Lunde posted an update 1 month ago

    Temperature plays an important role in Betanodavirus infection (Chi et al., 1999; Nishizawa et al., 2012; Oh et al., 2013). Some experiments have revealed that the temperature has no effect on Betanodavirus attachment to host (Chi et al., 1999; Hata et al., 2010). Indeed our results show that all the challenged fish became infected whatever…[Read more]

  • In this study we wished to confirm and expand upon observations that sfRNA is an RNAi suppressor (Schnettler et al., 2012). Using viral infections, we demonstrate a mild but statistically significant suppression of siRNA-mediated RNAi in both Dengue virus type 2 (DENV-2) and KUNV infected human cells. Importantly, dsRNA-mediated knockdown of gene…[Read more]

  • ResultsThe investigated DNA Damage DNA Repair Library show Raman bands between 375 and 50cm1 (Figs. 1–4, Table 1), where the cut-off value of the employed Raman notch and edge filters determine the low-energy limit. The Raman bands in the boulangerite spectra occur in the vibrational region between 375 and 50cm1 (Fig. 1, Table 1), with no a…[Read more]

  • Tick counts may indicate an animal’s level of infestation. According to Gonzales (2003), counts from 1 to 5 indicate mild infestation, 5 to 20 indicate moderate infestation, 20 to 50 indicate high infestation, and over 50 indicate a very high infestation. The results indicated mild to moderate tick infestations in the evaluated herd from 146 to…[Read more]

  • Plasma concentrations of cefovecin and AUC were both dose dependent, after SC and IM administrations. There were no evident differences between animal groups (females vs. males; young vs. adults). No major differences could be observed between cefovecin concentrations obtained after SC and IM administrations at doses of 1 or 2 mg/kg BW. The m…[Read more]

  • Here, we sought to identify the genes required for A. hydrophila infection in T. thermophila, with the ultimate goal of elucidating the mechanisms underlying pathogenesis in this multi-host opportunistic pathogen. Chinese epidemic A. hydrophila strain NJ-35, which belongs to the ST251 clonal group, was used as the wild-type strain to construct the…[Read more]

  • Viruses sharing a close genetic relationship also diverged into different antigenic groups. For instance, Ck/GD/01/11 and Ck/JL/0519/12 both belong to clade 6 but fall into antigenic groups D and E, respectively. This discrepancy may be due to the relationship between antigenic change and genetic change being nonlinear below the clade level…[Read more]

  • The previous report (Catania et al., 2010), indicated a decrease of average egg weight in the affected house, and improvement was seen after antibiotic treatment. In our study we confirm the field data regarding a negative impact on the average egg weight of infected hens, and in addition we noticed, a drop of egg numbers laid per week per hen…[Read more]

  • Accuracy of diagnostic PCR assays was assessed on DNA samples extracted from the blood of 46 bovines (23 positive and 23 negative in TvPRAC PCR) collected during an epidemiological survey in Ethiopia. Details on these samples have been published previously (Fikru et al., 2012). The following diagnostic PCR assays were tested without and with the…[Read more]

  • Hilton Lunde posted an update 2 months ago

    Gypsum may also be the result of alteration of calcium compounds due to the effect of sulphur-based pollutants (definitely present, at least since the 20th century, in the urban centre of Milan): in this case the attack was moderate and cannot be considered pathological, since it did not significantly affect the thymidine phosphorylase of the…[Read more]

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