Sepp Miles

  • Sepp Miles posted an update 1 month ago

    The AE damage detection of concrete structures has been analyzed by data parameters in AE signal. The AE signal was produced and recorded from transducers during the testing process. The parameters recorded in the AE win software are count, hit, amplitude, frequency, signal strength, absolute energy and energy. Each of them represented the…[Read more]

  • Sepp Miles posted an update 1 month ago

    For spirochetes, only Treponema denticola was identified in this study. This finding was consistent with that reported by Moter et al and further strengthened the hypothesis that Treponema are opportunistic pathogens. Olsenella species shows disease associations similar to those observed for lactobacilli in the oral cavity.Olsenella is a new…[Read more]

  • Sepp Miles posted an update 1 month, 1 week ago

    It is notable that the sera that preferentially recognized the PNG 301 loss mutant Du156332 and the sera that preferentially recognized the PNG 301 loss mutant, Du156334 overlapped surprisingly little (Fig. 7). There are two main explanations for this that are not mutually exclusive. Either the region exposed by removing the 301 glycan is…[Read more]

  • Sepp Miles posted an update 1 month, 1 week ago

    Figure  2 shows unadjusted mean min/wk of self-reported MVPA after completion of the 6-month intervention. Mean MVPA at 6 months ranged from 73.0 min/wk in Seamos Saludables to 169.7 min/wk in Activas. When data was aggregated across studies, there was a marginal overall effect of demonstration walk (b=24.9, SE=12.5, p=0.06). Looking at study pa…[Read more]

  • Sepp Miles posted an update 1 month, 1 week ago

    Despite its importance in both humans and animals, the epidemiological features of yersiniosis are still not completely understood. The reservoir of this disease has not yet been identified. However, several authors have suggested the role of rodents or wild Quinacrine Dihydrochloride in the dissemination of this disease (Fredriksson-Ahomaa et…[Read more]

  • Sepp Miles posted an update 1 month, 1 week ago

    Control of fleas and ticks is based principally on the use of parasiticides and the most widely used products are effective against both fleas and ticks. Various delivery systems and formulations are available including collars, spot-on’s, sprays and oral formulations (Beugnet and Franc, 2012). Treatment of dogs with spot-on formulations p…[Read more]

  • Sepp Miles posted an update 1 month, 1 week ago

    AcknowledgmentThe authors wish to extend their appreciation to the Deanship of Scientific Research at King Saud University for funding the work through the research group Project No. RGP-VPP-238.IntroductionInsulin-like growth factor binding proteins (IGFBPs) belong to a family of at least six homologous proteins that bind insulin-like growth…[Read more]

  • Sepp Miles posted an update 1 month, 2 weeks ago

    ConclusionsConflict of interest statementIntroductionFlupirtine (FLU) is an aminopyridine drug (ethyl 2-amino-6-[(4-fluorobenzyl)amino]pyridin-3-yl carbamate) approved in Europe in 1984 for the treatment of pain (Kumar et al., 2013). FLU is a centrally acting analgesic with a mechanism of action unlike that of opiates and non-steroidal…[Read more]

  • Sepp Miles posted an update 1 month, 2 weeks ago

    Another potential mechanism regulating the stability of tax/rex mRNA is nonsense-mediated decay (NMD), a process which poses a serious handicap for viruses such as HTLV-1, with multiple overlapping reading frames and premature termination codons. NMD is inhibited in HTLV-1 constitutively-expressing cell lines, including HUT102, and tax/rex as well…[Read more]

  • Sepp Miles posted an update 1 month, 2 weeks ago

    The use of EBM instead of AF-12 resulted in a more consistent VEC phenotype, as evidenced by enhanced endothelial marker expression and decreased α-SMA and SMemb expression. However, EBM did not inhibit the proliferation of contaminating cell types. A combination of cell sorting and of a specific endothelial medium culture could improve the…[Read more]

  • Sepp Miles posted an update 1 month, 2 weeks ago

    AcknowledgmentsWe thank Febe Elena Cázares Raga and Fidel de la Cruz Hernández-Hernández for their advice on the proteomic studies, Blanca Ramírez Herrera for technical assistance, Arturo Perez-Taylor for informatics and art design and Emma Saavedra Lira for reviewing the English language. This work was supported by Conacyt grant No. G38…[Read more]

  • Sepp Miles posted an update 1 month, 3 weeks ago

    Computational detailsAll the quantum chemical computations were carried out using the Gaussian 09 program [8] package using the B3LYP method with cc-pVTZ [9] as basis set. The Raman activities () calculated with the Gaussian 09 program have been suitably adjusted in the scaling procedure with MOLVIB and then converted to relative Raman…[Read more]

  • Sepp Miles posted an update 1 month, 3 weeks ago

    Though the complete ChHV5 genome was recently sequenced (Ackermann et al., 2012), and though various partial sequences of this virus have been provided from samples around the world, little is known about ChHV5 and its circulation. Various hypotheses have been developed regarding ChHV5 and its hosts. Patricio et al. (2012) established that the…[Read more]

  • Sepp Miles posted an update 1 month, 3 weeks ago

    IntroductionInfluenza A viruses (IAVs) contain a segmented genome composed of eight single-stranded RNA molecules with negative polarity and are classified in subtypes based on the combination of the two glycoproteins present in the virus envelope named hemagglutinin (HA) and neuraminidase (NA) (Palese and Shaw, 2007). HA and NA are the major…[Read more]

  • Sepp Miles posted an update 1 month, 4 weeks ago

    RNA was extracted from tissues using TRIzol (Invitrogen) and DNA was extracted using the DNeasy Blood and Tissue kit (Qiagen). Samples were first tested by reverse transcriptase (RT) real-time quantitative PCR (RT-qPCR) for FMDV. If negative in this test, samples were tested by PCR, RT-PCR or RT-qPCR using the protocol for differential diagnostics…[Read more]

  • Sepp Miles posted an update 2 months ago

    As the first line of defense, innate immunity plays an important role in anti-viral infection of host. PRRSV has been shown to evolve effective strategies to evade host immune surveillance including the innate and adaptive immune responses (Buddaert et al., 1998; Calzada-Nova et al., 2011; Darwich et al., 2010; Luo et al., 2008; Yoo et al., 2010).…[Read more]

  • We measured the expression of IL-1β, IL-6 and TNFα mRNA in liver tissue. The expression of both IL-1β and IL-6 mRNA in liver tissue was significantly greater in dogs with CPSS compared to Beagle control dogs. IL-1β, IL-6 and TNFα are inflammatory cytokines that are released by Kupffer l-ascorbic acid in response to stimulation by LPS (Shi…[Read more]

  • In the analysis of the HRM melting assay reproducible difference graphs of the four reference strains, as well as for the 22 additional B. hampsonii strains, were obtained. None of the 897 Swiss fecal isolates yielded a typical melting curve. Interestingly, all representatives of the four different genetic groups seem to form distinct groups…[Read more]

  • The Drenchrite test, developed in Australia in the 1990s as a resistance detection tool, provides a means to compare our drug selected isolate with field-derived levamisole-resistant worms. The test was based on the use of the LDA to test the sensitivity of the larval stages of trichostrongylid worms to various anthelmintic drugs (as described by…[Read more]

  • Sepp Miles posted an update 3 months ago

    There was a significant difference in DLA homozygosity between groups. Without pedigrees or breeding strategy information, we can only hypothesise that this high frequency of homozygosity within the pet Beagles might indicate a higher degree of inbreeding and/or a potential dominant sire effect. Homozygosity appears to vary between dog breeds,…[Read more]

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