Isaac Merritt

  • The peripheral immune response during the final term of fructose 1 6 bisphosphatase (G3) was similar to those observed for G1 and G2. However, it was characterized by an earlier IFN-γ response and lower peripheral immune response. The placental immune response had also less magnitude in G3 than in goats that gave birth from G2. Low immune system…[Read more]

  • Ectoparasite infection also generally leads to osmotic stress and poorer fish condition, resulting in susceptibility to secondary infections (Dawson et al., 1999; Wells et al., 2006). The present work is the first to experimentally assess the effects of C. rogercresseyi infection on the lactate responses of Atlantic and Coho salmon over time. This…[Read more]

  • IntroductionPrion diseases (or transmissible spongiform encephalopathies) are a unique group of subacute, fatal, infectious neurodegenerative disorders. During prion disease, aggregations of PrPSc, an abnormally folded isoform of the host cellular prion glycoprotein (PrPC) accumulate in affected tissues (Prusiner, 1982). Prion infectivity…[Read more]

  • Isaac Merritt posted an update 3 months ago

    In previous studies, we found that rapid proliferation was the main physiologic characteristic of the A. baumannii CCGGD201101 strain. In this study, we speculated that the rapid proliferation of A. baumannii was closely related to its virulence effect. Bacterial proliferation has been reported as a virulence effect of A. baumannii (Eveillard et…[Read more]

  • Isaac Merritt posted an update 3 months ago

    Viral fusion proteins fall into a small number of structural histone demethylase inhibitor – three reasonably well characterized ones at the time of this review (Harrison, 2008). The first of these three includes many of the best studied human pathogens, such as influenza virus (Skehel and Wiley, 2000) and HIV-1 (Chan and Kim, 1998). The p…[Read more]

  • Conflict of interest statementAcknowledgementsIntroductionWest Nile virus (WNV) is the most worldwide distributed flavivirus. Its transmission cycle involves ornithophilic mosquito-vectors and birds, although the virus occasionally infects other vertebrates, including humans and horses, in which it may cause sporadic disease outbreaks that may…[Read more]

  • AcknowledgmentsWe thank Dr. Heather Fleming for significant assistance in manuscript preparation, and Dr. Andrea Branch for valuable advice on experimental design. Further, we thank Dr. Alice Chen, Dr. Tal Danino, and Dr. Sabine Hauert for insightful discussions, and Eliza Vasile at the Koch Institute Microscopy center for help with SIM…[Read more]

  • Conflict of interest statementAcknowledgementsWe thank the Austrian Buiatrics Association for financial support of this study, and involved farmers and claw trimmers for their cooperation.Contagious agalactia (CA) is the most serious disease affecting small dairy ruminants (). CA is caused by four species of , namely, .  (the classic agent of the…[Read more]

  • An exact dose for COWP treatment in lambs has not been established (Knox, 2002; Burke et al., 2004; Fleming et al., 2006; Hale et al., 2007; Terrill et al., 2012). Doses investigated range from 0.5–6g of copper in various studies cited, using both sheep and goats (Burke and Miller, 2006). Copper toxicity is an obvious concern in sheep as they a…[Read more]

  • Isaac Merritt posted an update 4 months ago

    Dromedaries (Camelus dromedaries) are considered to be a good source of milk and meat, and are used for other purposes such as transportation and sport racing (Abbas et al., 2013). In the wake of global threats occasioned by climate change, the need for research to improve and diversify camel production is urgent. Trends indicate that camel…[Read more]

  • AcknowledgmentsThis work was supported by operating grants from the Canadian Institutes of Health Research (Grant number FRN 12172) and Alberta Innovates – Health Solutions. JRS is a Tier 1 Canada Research Chair in Molecular Virology. The funders played no role in the study design, collection, analysis and interpretation of data, writing of the r…[Read more]

  • Influenza A viruses of the H5 subtype are usually detected in low prevalence from dabbling ducks and often account for <1% of detected IAVs (Wilcox et al., 2011). However, local variation in the prevalence of H5 IAVs in ducks has been reported (Lindsay et al., 2013). The high H5 antibody prevalence we detected in Canada geese is not understood,…[Read more]

  • As well as being affected by the presence of organic matter and, potentially, temperature, the activity of disinfectants can also be affected by pH, with the activity of phenols/cresols, hypochlorites and iodides reported to decrease as environmental pH increases, and activity of QACs and aldehydes reported to increase (Maillard, 2013). The pH of…[Read more]

  • Isaac Merritt posted an update 5 months ago

    The main goal of this aldehyde dehydrogenase article is to demonstrate how a distributed approach based on V2V communications provided by CV technology can be used to mitigate the FCE. Our distributed TrafficEQ system combines traffic information crowd-sourcing via V2V communication with autonomous route guidance, in which a route choice is made…[Read more]

  • Figure 2. Representative sequential chest radiographs and the graphs of excursion and peak motion of the diaphragms obtained by chest dynamic radiography (“dynamic X-ray phrenicography”). (a) Radiograph of the resting end-expiratory position. (b) Radiograph of the resting end-inspiratory position. (c) Graph showing the vertical excursions and the…[Read more]

  • Our study demonstrated that the average excursions of the bilateral arginase inhibitor during tidal breathing (right: 11.0 mm, 95% CI 10.4 to 11.6 mm; left: 14.9 mm, 95% CI 14.2 to 15.5 mm) were numerically less than those during forced breathing in previous studies using other modalities 2; 7 ;  8. Using fluoroscopy, Alexander reported that the…[Read more]

  • Multiple linear regression analysis using all variables as factors (Model 1) demonstrated that weight, BMI, and tidal volume were independently associated with the bilateral excursion of the diaphragms (all P < 0.05) after adjusting for other clinical variables, including age, gender, smoking history, height, VC, %VC, FEV1, FEV1%, and %FEV1. There…[Read more]

  • Pulmonary Function TestsThe pulmonary function tests were performed in all participants on the same day of the imaging study. Parameters of pulmonary function tests were measured according to the American Thoracic Society guidelines 20 ;  21 using a pulmonary function instrument with computer processing (DISCOM-21 FX, Chest MI Co, Tokyo,…[Read more]

  • Figure 1. Flow diagram of the study population.Figure optionsDownload full-size imageDownload high-quality image (83 K)Download as PowerPoint slideImaging Protocol of Dynamic Chest Radiology (“Dynamic X-Ray Phrenicography”)Posteroanterior dynamic chest radiography (“dynamic X-ray phrenicography”) was performed using a prototype system (Konica…[Read more]

  • Pulmonary Function TestsThe pulmonary function tests were performed in all participants on the same day of the imaging study. Parameters of pulmonary function tests were measured according to the American Thoracic Society guidelines 20 ;  21 using a pulmonary function instrument with computer processing (DISCOM-21 FX, Chest MI Co, Tokyo,…[Read more]

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